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M  ›  machinate
M  ›  machinate
1828 Definition

MACH'INATE, v.t. [L. machinor.]

To plan; to contrive; to form a scheme.

1913 Definition
Machinate (machinate)
v. i.(?)
Mach"i*nate
[imp. *** p. p. Machinated (?)] p. pr. *** vb. n. Machinating (?).] [L. machinatus, p. p. of machinari to devise, plot. See Machine.]
  1. To plan] to contrive; esp., to form a scheme with the purpose of doing harm; to contrive artfully; to plot.
    "How long will you machinate!" Sandys.
  2. To contrive, as a plot; to plot; as, to machinate evil.

1828 dictionary
Noah Says...
They choose men, not because they are just men, men of religion and integrity, but solely for the sake of supporting a party. This is a fruitful source of public evils. But as surely as there is a God in heaven, who exercises a moral government over the affairs of this world, so certainly will the neglect of the divine command, in the choice of rulers, be followed by bad laws and as bad administration; by laws unjust or partial, by corruption, tyranny, impunity of crimes, waste of public money, and a thousand other evils. Men may desire and adopt a new form of government; they may amend old forms, repair breaches and punish violators of the constitution; but there is, there can be no effectual remedy, but obedience to the divine law.
 Value of the Bible (unpublished manuscript) :: 1834 




Myopia is generally what happens when unprecedented opportunities are placed before them. Those in the know generally do better than those in the worry. Consider Cetus, a startup biotech with a focus on a liver drug. The FDA delayed the approval of the drug, and a major funding crisis ensued. Chiron offered to take over the liabilities contingent on the sale of two patents (# 4,683,202 and # 4,683,195) to a third party, Roche Molecule for $300M (in 1993). This sale was stalled because DuPont challenged the validity of the patents, based on the formal claims written by the inventor (not a patent attorney), Kary Mullis. In the end, the soap opera turned out well for the investors with weak constitutions. For $300M, they sold the two patents to Roche, turned the company over to Chiron, and walked away. Kary Mullis won the Nobel prize for his invention embedded in these two patents, known as polymerase chain reaction (PCR) which allows DNA to be cloned. Over 4000 patents in biotech cite these original two patents. In our estimation, $300M represents "pennies on the dollar" valuation of these patents. The shareholders got a payday, and left the game. Roche on the other hand is thriving based on its intangible assets. Let IPstreet.com assist you.




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